Single nucleotide polymorphisms and recombination rate in humans :: Biology Genetic Diversity

Humans have many of the same genes except in like manner a lot of contractable variation. Therefore, gene sequencing is different in everyone. This genetic variation cracks a persons eye color, hair color, and other traits. However, this is also why some people get diseases and others dont. In a chromosome, the duration from the centromere dictates the consecrate of recombination. There is less shuffling in the sphere around the centromere, so that leads to less variation. However, understanding variation is necessary in order to determine abnormal genes. A single gene is the base of operations for identifying the abnormality. By looking at non-random sites with gene differentiations, one can determine the gene that causes the disease. There is more variation in regions with recombination, which happens in meiosis. The rate at which the crossing oer occurs varies, and this affects the variation present.Shuffling is not the alone determinant for variation in a gene. Selection also plays a role. For example, A gene is superior to B gene. C gene is committed to A gene through genetic hitchhiking. If A gene is selected over B gene, C gene is also expressed frequently. This is known as genetic hitchhiking. A biological application of this is the malaria gene. The colorblindness gene is hitchhiked onto the malaria insubordinate gene. Therefore, when a person receives the malaria resistant gene they also receive the colorblindness gene. As a result, colorblindness occurs more frequently in places where malaria is affluent because the people who dont receive the malaria resistant gene die and the people who be resistant and colorblind live and progress to on their genes.ImplicationsThe main implication of this experiment is that comparing the differences in the versatile genotypes of humans can illustrate genetic diseases. For example if a undecided has a certain genetic disease, this paper states that you could compargon the afflicted subjects genome to an independent persons genome and determine the location of the disease on the chromosome. If the location of genetic diseases are found then it is conceivable to screen fetuses for genetic diseases. This brings up estimable issues, would you want to know if your child has an incurable genetic disease? If genetic diseases are detected in a fetus then it may be possible to someday perform gene therapy. Gene therapy is the interposition of a genetic disease by providing patients with cells containing harmless and functional alleles for genes that are nonfunctional in their bodies.